Expresión de búsqueda: GROWTH DIFFERENTIATION FACTOR 1 
Descriptores Encontrados: 1
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Descriptor Inglés:   Growth Differentiation Factor 1 
Descriptor Español:   Factor 1 de Diferenciación de Crecimiento 
Descriptor Portugués:   Fator 1 de Diferenciação de Crescimento 
Categoría:   D12.644.276.954.300.100
D12.644.276.954.550.100
D12.776.467.942.300.100
D12.776.467.942.550.100
D23.529.942.300.100
D23.529.942.550.100
Definición Inglés:   A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS. 
Nota Histórica Inglés:   2009(2005) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   53139 
Identificador Único:   D055452 

Ocurrencia en la BVS:
 

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